Placebo response rate in patients with chronic constipation

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چکیده

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Treatment of chronic constipation with cisapride and placebo.

The effect of cisapride (20 mg bid), a new prokinetic drug, on bowel habits and laxative consumption was studied in patients with idiopathic painless constipation and chronic laxative intake. After a four week base line period, spontaneous defection (frequency without laxative intake) and total defecation (total frequency) were measured. Patients with a spontaneous defecation of less than three...

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Psychological disorders in patients with chronic constipation

AIM The aim of present study was to screen two categories of psychiatric disorders in chronic functional constipation. BACKGROUND It has been established that the prevalence of mood and anxiety disorders among patients with functional gastrointestinal disorders is higher than in the general population. PATIENTS AND METHODS Fifty four constipated patients were recruited from patients referre...

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psychological disorders in patients with chronic constipation

aim : the aim of present study was to screen two categories of psychiatric disorders in chronic functional constipation. background : it has been established that the prevalence of mood and anxiety disorders among patients with functional gastrointestinal disorders is higher than in the general population. patients and methods : fifty four constipated patients were recruited from patients refer...

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The efficacy of cisapride vs. placebo and diet in patients with chronic constipation.

The effects of cisapride (10 mg three times daily) on the stool evacuation characteristics, laxative consumption (symptom diary) and motility pattern (rectoanal manometry) were assessed in patients with chronic idiopathic constipation who fulfilled Rome II criteria. After a 14-day basal period on a diet rich in fiber (phase I), patients were treated with placebo (n = 20) or cisapride (n = 19) (...

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Evaluation of Immunohistochemistry (IHC) in Children with Chronic Constipation

Introduction Constipation is one of the most common causes of referral to pediatric gastroenterology clinics. The histopathology and Immunohistochemistry (IHC) studies indicated that several neurons are currently detectable in motility of the gut. We aimed to evaluate calretinin in the children with chronic constipation. Materials and Methods In this cohort study, 40 children with chronic const...

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ژورنال

عنوان ژورنال: Medicine

سال: 2020

ISSN: 0025-7974,1536-5964

DOI: 10.1097/md.0000000000019020